Saijo Lab Research Articles

“Activity-Based Sensing with a Metal-Directed Acyl Imidazole Strat-egy Reveals Cell Type-Dependent Pools of Labile Brain Copper.
Lee S, Chung C, Liu P, Craciun L, Nishikawa Y, Bruemmer K, Hamachi I, Saijo K, Miller E, Chang C. J. Am. Chem. Soc. 2020

Phf15 – a novel transcriptional repressor regulating inflammation in a mouse microglial cell line.”
Muroy SE, Timblin GA, Preininger MK, Cedillo P, Saijo K. Neuroimmunol Neuroinflammation 2020;7:166-182.

“Versatile Histochemical Approach to Detection of Hydrogen Peroxide in Cells and Tissues Based on Puromycin Staining.”
Yik-Sham Chung C, Timblin GA, Saijo K, Chang CJ.  J Am Chem Soc. 2018;140(19):6109-6121.

“Actomyosin-Mediated Tension Orchestrates Uncoupled Respiration in Adipose Tissues.”
Tharp KM, Kang MS, Timblin GA, Jon DempersmierGarret E DempseyPeter-James H ZushinJaime BenavidesCatherine ChoiCatherine X LiAmit K JhaShingo KajimuraKevin E HealyHei Sook SulKaoru SaijoSanjay KumarAndreas Stahl. 
Cell Metab. 2018;27(3):602-615.e4.

“An ERb-CtBP transrepression pathway negatively regulates microglia-mediated inflammation.”
Saijo K, Collier JG, Li AC, Katzenellenbogen JA, Glass CK. (2011) Cell 145:584-95

“Coronin2A mediates actin-dependent de-repression of inflammatory response genes.”
Huang W, Ghisletti S, Saijo K, Gandhi M, Aouadi M, Tesz G, Zhang D, Yao J, Czech M, Goode BL, Rosenfeld MG, Glass CK (2011) Nature 470:414-8

“The nuclear receptor PPARg controls TH17 differentiation and suppresses TH17 dependent autoimmunity.”
Klotz L, Burgdorf S, Dani I, Saijo K, Alferink J, Langhans B, Klockgether T, Frommer F, Cherrier M, Waisman A,  Eberl G, Glass CK, Kurts C and Knolle P. (2009) J Exp Med 206: 2079-89

“A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death.”
Saijo K, Winner B, Carson CC, Collier JG, Boyer L., Rosenfeld MG, Gage FH, Glass CK. (2009) Cell 137: 47-59

“Expression Analysis of G Protein-Coupled Receptors in Mouse Macrophages.”
Lattin JE, Schroder K, Su AI, Walker JR, Zhang J, Wiltshire T, Saijo K, Glass CK, Hume DA, Kellie S, Sweet MJ. (2008)  Immunome Research 4:5

Saijo Lab Review Articles

“The Endocannabinoid System as a Window Into Microglial Biology and Its Relationship to Autism.” Araujo DJ, Tjoa K, Saijo K. Front Cell Neurosci. 2019;13:424. Published 2019 Sep 18.

“Regulation of microglia activation and de-activation by nuclear receptors.”

Saijo K
, Crotti A, Glass CK (2013) GLIA 61:104-11

“Microglial cell origin and phenotypes in health and disease”
Saijo K,
Glass CK (2011) Nature Reviews Immunology. 11:775-87

“Nuclear receptors, Inflammation and Neurodegenerative Disease”
Saijo K
, Crotti A, Glass CK (2010)  Advances in Immunology 106:21-59

“Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cell.”
Glass CK, Saijo K. (2010)  Nature Reviews Immunology. 10:365-76

“Mechanisms underlying inflammation in neurodegeneration.”
Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH (2010)  Cell 140:918-934

“Immunology: Oxysterols hold T cells in check.”
Glass CK, Saijo K. (2008)  Nature 455:40-1

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